- Escitalopram versus other antidepressive agents for depression
Cochrane Systematic Reviews, 15-Apr-2009
Although pharmacological and psychological interventions are both effective for major depression, antidepressant drugs remain the mainstay of treatment in primary and secondary care settings. During the last 20 years, antidepressant prescribing has risen - Eslicarbazepine acetate add‐on therapy for drug‐resistant focal epilepsy
Cochrane Systematic Reviews, 22-Jun-2021
This is an update of a review first published in 2011, and last updated in 2017. - Estrogen for schizophrenia
Cochrane Systematic Reviews, 10-Nov-2009
In terms of clinical outcomes, women with schizophrenia seem to fare better then men, but appear more vulnerable to psychotic illness in the period after birth and menopause. As these vulnerable periods to psychosis are associated with estrogen withdrawal - Eszopiclone for insomnia
Cochrane Systematic Reviews, 10-Oct-2018
Insomnia is a major public health issue affecting between 6% to 10% of the adult population in Western countries. Eszopiclone is a hypnotic drug belonging to a newer group of hypnotic agents, known as new generation hypnotics, which was marketed as being - Etanercept for the treatment of rheumatoid arthritis
Cochrane Systematic Reviews, 2-Apr-2013
Etanercept is a soluble tumour necrosis factor alpha-receptor disease-modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). - Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants
Cochrane Systematic Reviews, 20-Jan-2010
Ethamsylate decreases blood loss in certain clinical situations such as menorrhagia and following some surgical procedures. This potential to reduce bleeding has led to the hypothesis that it may have a role to play in reducing intraventricular haemorrhag - Ethanol for preventing preterm birth in threatened preterm labor
Cochrane Systematic Reviews, 3-Nov-2015
Preterm birth is the leading cause of death and disability in newborns worldwide. A wide variety of tocolytic agents have been utilized to delay birth for women in preterm labor. One of the earliest tocolytics utilized for this purpose was ethanol infusio - Ethical case interventions for adult patients
Cochrane Systematic Reviews, 22-Jul-2019
Decisions in clinical medicine can be associated with ethical challenges. Ethical case interventions (e.g. ethics committee, moral case deliberation) identify and analyse ethical conflicts which occur within the context of care for patients. Ethical case - Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents
Cochrane Systematic Reviews, 21-Jan-2021
This is an updated version of the Cochrane Review previously published in 2019. - Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 23-Jan-2008
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts. - Etrolizumab for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 2-Dec-2015
Etrolizumab (rhuMAb beta7) is an anti-integrin that selectively targets the ß7 subunits of the a4ß7 and aEß7 integrins, which are involved in the pathogenesis of ulcerative colitis. - Evaluation of follow‐up strategies for patients with epithelial ovarian cancer following completion of primary treatment
Cochrane Systematic Reviews, 8-Sep-2014
Ovarian cancer is the sixth most common cancer and seventh commonest cause of death in women worldwide. Traditionally, many people who have been treated for cancer undergo long-term follow-up in secondary care. However, it has been suggested that the use - Evaluation of the efficacy and safety of adjuvant treatment to levodopa therapy in Parkinson´s disease patients with motor complications
Cochrane Systematic Reviews, 17-Jun-2010
One of the complications of long-term treatment of Parkinson's disease (PD) with levodopa is the development of motor complications. Generally, when motor complications develop, clinicians add in an additional drug (to the levodopa regimen) from one of th - Evening versus morning dosing regimen drug therapy for hypertension
Cochrane Systematic Reviews, 22-Sep-2011
Variation in blood pressure levels display circadian rhythms. The morning surge in blood pressure is known to increase the risk of myocardial events in the first several hours post awakening. A systematic review of the administration-time-related-effects - Eversion versus conventional carotid endarterectomy for preventing stroke
Cochrane Systematic Reviews, 23-Oct-2000
Carotid endarterectomy (CEA) is conventionally undertaken by a longitudinal arteriotomy. Eversion CEA, which employs a transverse arteriotomy and reimplantation of the carotid artery, is reported to be associated with low perioperative stroke and restenos - Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
Cochrane Systematic Reviews, 17-Jun-2014
Myopia is a condition in which the focusing power (refraction) of the eye is greater than that required for clear distance vision. There are two main types of surgical correction for moderate to high myopia; excimer laser and phakic intraocular lenses (IO - Excisional surgery versus ablative surgery for ovarian endometriomata
Cochrane Systematic Reviews, 13-Apr-2011
Endometriomata are endometriotic deposits within the ovary. The surgical management of these blood filled cysts is controversial. The laparoscopic approach to the management of endometriomata is favoured over a laparotomy approach as it offers the advanta - Excitatory amino acid antagonists for acute stroke
Cochrane Systematic Reviews, 21-Jul-2003
Focal cerebral ischaemia causes release of excitatory amino acid (EAA) neurotransmitters, principally glutamate, with resultant over-stimulation of EAA receptors and downstream pathways. Excess glutamate release is a pivotal event in the evolution of irre - Excitatory amino acid inhibitors for traumatic brain injury
Cochrane Systematic Reviews, 20-Jan-2003
Glutamate is the principal excitatory neurotransmitter in the brain. Injury to the brain can cause an ionic imbalance in cerebral tissue, creating an excitotoxic cascade involving glutamate and other excitatory amino acids, that leads to neuronal death in - Exenterative surgery for recurrent gynaecological malignancies
Cochrane Systematic Reviews, 21-Sep-2016
Cancer is a leading cause of death worldwide. Gynaecological cancers (i.e. cancers affecting the ovaries, uterus, cervix, vulva and vagina) are among the most common cancers in women. Unfortunately, given the nature of the disease, cancer can recur or pro
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