- Enteral nutritional therapy for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 1-Apr-2018
Corticosteroids are often preferred over enteral nutrition (EN) as induction therapy for Crohn's disease (CD). Prior meta-analyses suggest that corticosteroids are superior to EN for induction of remission in CD. Treatment failures in EN trials are often - Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 19-Jan-2011
Enteral feeding (tube feeding) is offered to many people with amyotrophic lateral sclerosis/motor neuron disease experiencing difficulty swallowing (dysphagia) and maintaining adequate nutritional intake leading to weight loss. - Enteral tube feeding for cystic fibrosis
Cochrane Systematic Reviews, 22-Jul-2019
Enteral tube feeding is routinely used in many cystic fibrosis centres when oral dietary and supplement intake has failed to achieve an adequate nutritional status. The use of this method of feeding is assessed on an individual basis taking into considera - Enteral tube feeding for older people with advanced dementia
Cochrane Systematic Reviews, 15-Apr-2009
The use of enteral tube feeding for patients with advanced dementia who have poor nutritional intake is common. In one US survey 34% of 186,835 nursing home residents with advanced cognitive impairment were tube fed. Potential benefits or harms of this pr - Enteral tube feeding for people with severe dementia
Cochrane Systematic Reviews, 13-Aug-2021
The balance of benefits and harms associated with enteral tube feeding for people with severe dementia is not clear. An increasing number of guidelines highlight the lack of evidenced benefit and potential risks of enteral tube feeding. In some areas of t - Enteral versus parenteral nutrition and enteral versus a combination of enteral and parenteral nutrition for adults in the intensive care unit
Cochrane Systematic Reviews, 8-Jun-2018
Critically ill people are at increased risk of malnutrition. Acute and chronic illness, trauma and inflammation induce stress-related catabolism, and drug-induced adverse effects may reduce appetite or increase nausea and vomiting. In addition, patient ma - Enteral versus parenteral nutrition for acute pancreatitis
Cochrane Systematic Reviews, 20-Jan-2010
Acute pancreatitis creates a catabolic stress state promoting a systemic inflammatory response and nutritional deterioration. Adequate supply of nutrients plays an important role in recovery. Total parenteral nutrition (TPN) has been standard practice for - Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates
Cochrane Systematic Reviews, 12-Mar-2021
Preterm and low birth weight infants are born with low stores in zinc, which is a vital trace element for growth, cell differentiation and immune function. Preterm infants are at risk of zinc deficiency during the postnatal period of rapid growth. Systema - Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in older people with visual impairment
Cochrane Systematic Reviews, 3-Sep-2020
Impairment of vision is associated with a decrease in activities of daily living. Avoidance of physical activity in older adults with visual impairment can lead to functional decline and is an important risk factor for falls. The rate of falls and fractur - Environmental and behavioural modifications for improving food and fluid intake in people with dementia
Cochrane Systematic Reviews, 18-Jul-2018
Weight loss, malnutrition and dehydration are common problems for people with dementia. Environmental modifications such as, change of routine, context or ambience at mealtimes, or behavioural modifications, such as education or training of people with de - Environmental enrichment for stroke and other non‐progressive brain injury
Cochrane Systematic Reviews, 23-Nov-2021
Rehabilitation is effective for recovery after stroke and other non-progressive brain injuries but it is unclear if the rehabilitation environment itself, outside of limited therapy hours, is maximally conducive to recovery. Environmental enrichment is a - Environmental interventions to reduce the consumption of sugar‐sweetened beverages and their effects on health
Cochrane Systematic Reviews, 12-Jun-2019
Frequent consumption of excess amounts of sugar-sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environmen - Environmental sanitary interventions for preventing active trachoma
Cochrane Systematic Reviews, 15-Feb-2012
Trachoma is a major cause of avoidable blindness. It is responsible for about six million blind people worldwide, mostly in the poor communities of developing countries. One of the major strategies advocated for the control of the disease is the applicati - Enzyme replacement and substrate reduction therapy for Gaucher disease
Cochrane Systematic Reviews, 27-Mar-2015
Gaucher disease, a rare disorder, is caused by inherited deficiency of the enzyme glucocerebrosidase. It is unique among the ultra-orphan disorders in that four treatments are currently approved by various regulatory authorities for use in routine clinica - Enzyme replacement therapy for Anderson‐Fabry disease
Cochrane Systematic Reviews, 25-Jul-2016
Anderson-Fabry disease is an X-linked defect of glycosphingolipid metabolism. Progressive renal insufficiency is a major source of morbidity, additional complications result from cardio- and cerebro-vascular involvement. Survival is reduced among affected - Enzyme replacement therapy for infantile‐onset Pompe disease
Cochrane Systematic Reviews, 20-Nov-2017
Infantile-onset Pompe disease is a rare and progressive autosomal-recessive disorder caused by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). Current treatment involves enzyme replacement therapy (with recombinant human alglucosidase a - Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI
Cochrane Systematic Reviews, 17-Sep-2021
Mucopolysaccharidosis type VI (MPS VI) or Maroteaux-Lamy syndrome is a rare genetic disorder caused by the deficiency of arylsulphatase B. The resultant accumulation of dermatan sulphate causes lysosomal damage. - Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome)
Cochrane Systematic Reviews, 5-Feb-2016
Mucopolysaccharidosis II, also known as Hunter syndrome, is a rare, X-linked disease caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase, which catalyses a step in the catabolism of glycosaminoglycans. The glycosaminoglycans accumulate wi - Enzyme replacement therapy with laronidase (Aldurazyme®) for treating mucopolysaccharidosis type I
Cochrane Systematic Reviews, 18-Jun-2019
Mucopolysaccharidosis type I can be classified as three clinical sub-types; Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome, with the scale of severity being such that Hurler syndrome is the most severe and Scheie syndrome the least severe. It - Ephedrine for myasthenia gravis, neonatal myasthenia and the congenital myasthenic syndromes
Cochrane Systematic Reviews, 17-Dec-2014
Myasthenia is a condition in which neuromuscular transmission is affected by antibodies against neuromuscular junction components (autoimmune myasthenia gravis, MG; and neonatal myasthenia gravis, NMG) or by defects in genes for neuromuscular junction pro
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