- Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic kidney disease
Cochrane Systematic Reviews, 27-Oct-2020
Treatment with angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) is used to reduce proteinuria and retard the progression of chronic kidney disease (CKD). However, resolution of proteinuria may be incomplete with thes - Alemtuzumab for multiple sclerosis
Cochrane Systematic Reviews, 15-Apr-2016
Multiple sclerosis (MS) is an autoimmune, T-cell-dependent, inflammatory, demyelinating disease of the central nervous system, with an unpredictable course. Current MS therapies focus on treating exacerbations, preventing new exacerbations and avoiding th - Alemtuzumab for patients with chronic lymphocytic leukaemia
Cochrane Systematic Reviews, 15-Feb-2012
Chronic lymphocytic leukaemia (CLL) accounts for 25% of all leukaemias and is the most common lymphoid malignancy in Western countries. Standard treatment includes mono- or poly-chemotherapies. Nowadays, monoclonal antibodies are added, especially alemtu - alemtuzumab versus interferon beta 1a for relapsing‐remitting multiple sclerosis
Cochrane Systematic Reviews, 27-Nov-2017
Alemtuzumab is a humanised monoclonal antibody that alters the circulating lymphocyte pool, causing prolonged lymphopenia, thus remoulding the immune repertoire that accompanies homeostatic lymphocyte reconstitution. It has been proved more effective than - Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 11-Jul-2011
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Alendronate belongs to the bisphosphonate class of drugs, which act to inhibit bone resorption by interfering with the activity of osteoclasts. - Alexander technique for chronic asthma
Cochrane Systematic Reviews, 12-Sep-2012
'The Alexander technique' is a taught form of therapy involving a series of movements designed to correct posture and bring the body into natural alignment with the object of helping it to function efficiently, and is reported to aid relaxation. Some prac - Alginate dressings for healing diabetic foot ulcers
Cochrane Systematic Reviews, 25-Jun-2013
Foot ulcers in people with diabetes mellitus are a common and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from including alginate dressings. A clear and curr - Alginate dressings for treating pressure ulcers
Cochrane Systematic Reviews, 18-May-2015
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from incl - Alginate dressings for venous leg ulcers
Cochrane Systematic Reviews, 19-Aug-2015
Venous leg ulcers are a common and recurring type of chronic, complex wound associated with considerable cost to patients and healthcare providers. To aid healing, primary wound contact dressings are usually applied to ulcers beneath compression devices. - Algorithm‐based pain management for people with dementia in nursing homes
Cochrane Systematic Reviews, 1-Apr-2022
People with dementia in nursing homes often experience pain, but often do not receive adequate pain therapy. The experience of pain has a significant impact on quality of life in people with dementia, and is associated with negative health outcomes. Untre - Alkalinisation for organophosphorus pesticide poisoning
Cochrane Systematic Reviews, 24-Jan-2005
Poisoning with organophosphorus pesticides (OPs) is an important cause of morbidity and mortality worldwide, particularly in developing countries. The case-fatality for intentional self-poisoning is around 10 to 20% even when the standard antidotes (atrop - Alkylating agents for Waldenstrom's macroglobulinaemia
Cochrane Systematic Reviews, 21-Jan-2009
Waldenstrom's macroglobulinaemia (WM) is an uncommon B-cell lymphoproliferative disorder characterized by bone marrow infiltration and production of monoclonal immunoglobulin. Uncertainty remains if alkylating agents, such as chlorambucil, melphalan or cy - Allergen injection immunotherapy for seasonal allergic rhinitis
Cochrane Systematic Reviews, 24-Jan-2007
Allergic rhinitis is the most common of the allergic diseases. Despite improved understanding of the pathophysiology of allergic rhinitis and advances in its pharmacological treatment, its prevalence has increased worldwide. For patients whose symptoms re - Allergen-specific oral immunotherapy for peanut allergy
Cochrane Systematic Reviews, 14-Aug-2012
Peanut allergy is one of the most common forms of food allergy encountered in clinical practice. In most cases, it does not spontaneously resolve; furthermore, it is frequently implicated in acute life-threatening reactions. The current management of pea - Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission
Cochrane Systematic Reviews, 9-Aug-2011
Consolidation chemotherapy, autologous hematopoietic cell transplantation (HCT) and allogeneic HCT represent potential treatment alternatives for post-remission therapy in adult acute lymphoblastic leukemia (ALL), but there is genuine uncertainty regardin - Allogeneic stem cell transplantation versus conventional therapy for advanced primary cutaneous T‐cell lymphoma
Cochrane Systematic Reviews, 29-Aug-2013
Primary cutaneous T-cell lymphomas (CTCL) belong to the group of non-Hodgkin lymphomas and usually run an indolent course. However, some patients progress to advanced tumour or leukaemic stages. To date, there is no cure for those cases. In the last few y - Allopurinol for chronic gout
Cochrane Systematic Reviews, 14-Oct-2014
Allopurinol, a xanthine oxidase inhibitor, is considered one of the most effective urate-lowering drugs and is frequently used in the treatment of chronic gout. - Allopurinol for chronic prostatitis
Cochrane Systematic Reviews, 21-Oct-2002
Chronic prostatitis is a condition that causes men substantial morbidity through the associated constellation of urinary symptoms, sexual dysfunction, and pelvic pain. The etiology of chronic prostatitis is unknown, and the many and varied treatments for - Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic‐ischaemic encephalopathy
Cochrane Systematic Reviews, 11-Jul-2012
Delayed neuronal death following a perinatal hypoxic insult is due partly to xanthine oxidase-mediated production of cytotoxic free radicals. Evidence exists that allopurinol, a xanthine-oxidase inhibitor, reduces delayed cell death in experimental models - Almitrine-Raubasine combination for dementia
Cochrane Systematic Reviews, 15-Feb-2011
Almitrine-raubasine combination (brand name Duxil), has been considered as an alternative treatment for dementia.
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