- Drugs for treatment of very high blood pressure during pregnancy
Cochrane Systematic Reviews, 26-Jul-2013
Very high blood pressure during pregnancy poses a serious threat to women and their babies. The aim of antihypertensive therapy is to lower blood pressure quickly but safety, to avoid complications. Antihypertensive drugs lower blood pressure but their co - Drugs versus placebo for dysthymia
Cochrane Systematic Reviews, 18-Jun-2015
Dysthymia is a depressive disorder of chronic nature but of lower severity than major depression. Depressive symptoms are more or less continuous for at least two years. Patients with this disorder experience considerable social dysfunction and disability - Dual antibiotics for bronchiectasis
Cochrane Systematic Reviews, 29-May-2018
Bronchiectasis is a chronic respiratory disease characterised by abnormal and irreversible dilatation of the smaller airways and associated with a mortality rate greater than twice that of the general population. Antibiotics serve as front-line therapy fo - Dual chamber versus single chamber ventricular pacemakers for sick sinus syndrome and atrioventricular block
Cochrane Systematic Reviews, 25-Jun-2013
Dual chamber pacing or single chamber atrial pacing ('physiologic' pacing) is believed to have an advantage over single chamber ventricular pacing in that it resembles cardiac physiology more closely by maintaining atrioventricular (AV) synchrony and domi - Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis
Cochrane Systematic Reviews, 3-Dec-2018
Long-acting bronchodilators such as long-acting ß-agonist (LABA), long-acting muscarinic antagonist (LAMA), and LABA/inhaled corticosteroid (ICS) combinations have been used in people with moderate to severe chronic obstructive pulmonary disease (COPD) to - Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia
Cochrane Systematic Reviews, 23-Oct-2015
Duloxetine is a balanced serotonin and noradrenaline reuptake inhibitor licensed for the treatment of major depressive disorders, urinary stress incontinence and the management of neuropathic pain associated with diabetic peripheral neuropathy. A number o - Duloxetine versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 10-Sep-2012
Although pharmacological and psychological interventions are both effective for major depression, in primary and secondary care settings antidepressant drugs remain the mainstay of treatment. Amongst antidepressants many different agents are available. Du - Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis
Cochrane Systematic Reviews, 24-Mar-2016
Surgical excision by removal of the head of the pancreas to decompress the obstructed ducts is one of the treatment options for people with symptomatic chronic pancreatitis. Surgical excision of the head of the pancreas can be performed by excision of the - Duration of adjuvant chemotherapy for patients with non-metastatic colorectal cancer
Cochrane Systematic Reviews, 29-Oct-2009
Surgery of primary tumour is the backbone of colorectal cancer treatment (CRC). But in stage III cancer, metastatic or local relapse is often observed (50%). So, adjuvant treatment is always considered in this setting. The best treatment duration of hypot - Duration of antibacterial treatment for uncomplicated urinary tract infection in women
Cochrane Systematic Reviews, 28-Sep-2008
Uncomplicated urinary tract infection (UTI) is a common disease, occurring frequently in young sexually active women. In the past, seven day antibiotic therapy was recommended while the current practice is to treat uncomplicated UTI for three days. - Duration of intravenous antibiotic therapy in people with cystic fibrosis
Cochrane Systematic Reviews, 22-Aug-2019
Progressive lung damage from recurrent exacerbations is the major cause of mortality and morbidity in cystic fibrosis. Life expectancy of people with cystic fibrosis has increased dramatically in the last 40 years. One of the major reasons for this increa - Duration of treatment for asymptomatic bacteriuria during pregnancy
Cochrane Systematic Reviews, 4-Nov-2015
A previous Cochrane systematic review has shown that antibiotic drug treatment of asymptomatic bacteriuria in pregnant women substantially decreases the risk of pyelonephritis and reduces the risk of preterm delivery. However, it is not clear whether sing - Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Cochrane Systematic Reviews, 24-Jul-2014
Currently, the most frequently used secondary treatment for patients with venous thromboembolism (VTE) consists of vitamin K antagonists (VKA) targeted at an international normalized ratio (INR) of 2.5 (range 2.0 to 3.0). However, based on the continuing - Dynamic compression plating versus locked intramedullary nailing for humeral shaft fractures in adults
Cochrane Systematic Reviews, 3-May-2011
Surgical fixation of fractures of the shaft of the humerus generally involves plating or nailing. It is unclear whether one method is more effective than the other. - Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis
Cochrane Systematic Reviews, 11-Aug-2009
An up-to-date overview of the effectiveness and safety of dynamic exercise therapy (exercise therapy with a sufficient intensity, duration, and frequency to establish improvement in aerobic capacity and/or muscle strength) is lacking. - Dynamic exercise therapy for treating rheumatoid arthritis
Cochrane Systematic Reviews, 12-May-2009
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the musculoskeletal system. Inflammation of the joints and tendons results in pain, swelling and restricted movement, eventually leading to radiological changes and deformities. Exercis - Ear drops for the removal of ear wax
Cochrane Systematic Reviews, 31-Oct-2018
Problems attributed to the accumulation of wax (cerumen) are among the most common reasons for people to present to their general practitioners with ear trouble. Treatment for this condition often involves use of a wax softening agent (cerumenolytic) to d - Ear drops for the removal of ear wax
Cochrane Systematic Reviews, 8-Oct-2018
Ear wax (cerumen) is a normal bodily secretion that can become a problem when it obstructs the ear canal. Symptoms attributed to wax (such as deafness and pain) are among the commonest reasons for patients to present to primary care with ear trouble. - Early (< 8 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants
Cochrane Systematic Reviews, 23-Jan-2018
Bronchopulmonary dysplasia remains a major problem in neonatal intensive care units. Persistent inflammation in the lungs is the most likely underlying pathogenesis. Corticosteroids have been used to prevent or treat bronchopulmonary dysplasia because of - Early additional food and fluids for healthy breastfed full-term infants
Cochrane Systematic Reviews, 30-Aug-2016
Health organisations recommend exclusive breastfeeding for six months. However, the addition of other fluids or foods before six months is common in many countries. Recently, research has suggested that introducing solid food at around four months of age
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