- Effects of nonsteroidal anti‐inflammatory drugs on postoperative renal function in adults with normal renal function
Cochrane Systematic Reviews, 18-Apr-2007
Nonsteroidal anti-inflammatory drugs (NSAIDs) can play a major role in the management of acute pain in the peri-operative period. However, there are conflicting views on whether NSAIDs are associated with adverse renal effects. - Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea
Cochrane Systematic Reviews, 8-Jul-2015
Obstructive sleep apnoea (OSA) is a common sleep disorder characterised by partial or complete upper airway occlusion during sleep, leading to intermittent cessation (apnoea) or reduction (hypopnoea) of airflow and dips in arterial oxygen saturation durin - Effects of oral vitamin D supplementation on linear growth and other health outcomes among children under five years of age
Cochrane Systematic Reviews, 11-Dec-2020
Vitamin D is a secosteroid hormone that is important for its role in calcium homeostasis to maintain skeletal health. Linear growth faltering and stunting remain pervasive indicators of poor nutrition status among infants and children under five years of - Effects of peri‐operative nonsteroidal anti‐inflammatory drugs on post‐operative kidney function for adults with normal kidney function
Cochrane Systematic Reviews, 29-Nov-2018
Nonsteroidal anti-inflammatory drugs (NSAIDs) provide effective analgesia during the post-operative period but can cause acute kidney injury (AKI) when used peri-operatively (at or around the time of surgery). This is an update of a Cochrane review publis - Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes
Cochrane Systematic Reviews, 9-Jun-2015
Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes. - Effects of sevoflurane versus other general anaesthesia on emergence agitation in children
Cochrane Systematic Reviews, 9-Sep-2014
Sevoflurane is an inhaled volatile anaesthetic that is widely used in paediatric anaesthetic practice. Since its introduction, postoperative behavioural disturbance known as emergence agitation (EA) or emergence delirium (ED) has been recognized as a prob - Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants
Cochrane Systematic Reviews, 11-Apr-2017
The use of supplemental oxygen in the care of extremely preterm infants has been common practice since the 1940s. Despite this, there is little agreement regarding which oxygen saturation (SpO2) ranges to target to maximise short- or long-term growth and - Effects of total fat intake on body fatness in adults
Cochrane Systematic Reviews, 1-Jun-2020
The ideal proportion of energy from fat in our food and its relation to body weight is not clear. In order to prevent overweight and obesity in the general population, we need to understand the relationship between the proportion of energy from fat and re - Effects of total fat intake on body weight
Cochrane Systematic Reviews, 19-Aug-2016
In order to prevent overweight and obesity in the general population we need to understand the relationship between the proportion of energy from fat and resulting weight and body fatness in the general population. - Effects of total fat intake on bodyweight in children
Cochrane Systematic Reviews, 5-Jul-2018
As part of efforts to prevent childhood overweight and obesity, we need to understand the relationship between total fat intake and body fatness in generally healthy children. - Efficacy and experiences of telephone counselling for informal carers of people with dementia
Cochrane Systematic Reviews, 1-Sep-2014
Informal carers of people with dementia can suffer from depressive symptoms, emotional distress and other physiological, social and financial consequences. - Efficacy and safety of ablation for people with non-paroxysmal atrial fibrillation
Cochrane Systematic Reviews, 18-Nov-2016
The optimal rhythm management strategy for people with non-paroxysmal (persistent or long-standing persistent) atrial fibrilation is currently not well defined. Antiarrhythmic drugs have been the mainstay of therapy. But recently, in people who have not r - Efficacy and safety of cesarean delivery for prevention of mother‐to‐child transmission of HIV‐1
Cochrane Systematic Reviews, 19-Oct-2005
Cesarean section before labor and before ruptured membranes ("elective cesarean section", or ECS) has been introduced as an intervention for the prevention of mother-to-child transmission (MTCT) of HIV-1. The role of mode of delivery in the management of - Efficacy and safety of COVID‐19 vaccines
Cochrane Systematic Reviews, 7-Dec-2022
Different forms of vaccines have been developed to prevent the SARS-CoV-2 virus and subsequent COVID-19 disease. Several are in widespread use globally. - Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome
Cochrane Systematic Reviews, 15-Jun-2011
Alcohol abuse and dependence represents a very serious health problem worldwide with major social, interpersonal and legal interpolations. Pharmacological treatments presently used are of uncertain effectiveness and there is even more doubt on the compara - Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat
Cochrane Systematic Reviews, 4-Jun-2020
Sore throat is a common condition caused by viruses or bacteria, and is a leading cause of antibiotic prescription in primary care. The most common bacterial species is group A streptococcus (’strep throat’). Between 50% to 70% of pharyngitis cases are tr - Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults
Cochrane Systematic Reviews, 14-Aug-2017
Acetylcholinesterase inhibitors, such as neostigmine, have traditionally been used for reversal of non-depolarizing neuromuscular blocking agents. However, these drugs have significant limitations, such as indirect mechanisms of reversal, limited and unpr - Efficacy of psychostimulant drugs for amphetamine abuse or dependence
Cochrane Systematic Reviews, 30-Aug-2013
Amphetamine dependence is a public health problem with medical, psychiatric, cognitive, legal and socioeconomic consequences. To date, no pharmacological treatment has been approved for this disorder, and psychotherapy remains the mainstay of treatment. I - E‐Health interventions for anxiety and depression in children and adolescents with long‐term physical conditions
Cochrane Systematic Reviews, 15-Aug-2018
Long-term physical conditions affect 10% to 12% of children and adolescents worldwide; these individuals are at greater risk of developing psychological problems, particularly anxiety and depression. Access to face-to-face treatment for such problems is o - eHealth interventions for people with chronic kidney disease
Cochrane Systematic Reviews, 6-Aug-2019
Chronic kidney disease (CKD) is associated with high morbidity and death, which increases as CKD progresses to end-stage kidney disease (ESKD). There has been increasing interest in developing innovative, effective and cost-efficient methods to engage wit
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