- Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers
Cochrane Systematic Reviews, 14-Mar-2016
Extensive evidence shows that well over 50% of people prefer to be cared for and to die at home provided circumstances allow choice. Despite best efforts and policies, one-third or less of all deaths take place at home in many countries of the world. - Effectiveness and risks of cricoid pressure during rapid sequence induction for endotracheal intubation
Cochrane Systematic Reviews, 12-Nov-2015
Rapid sequence induction (RSI) for endotracheal intubation is a technique widely used in anaesthesia, emergency and intensive care medicine to secure an airway in patients deemed at risk of pulmonary aspiration. Cricoid pressure is conceptually used to re - Effectiveness and safety of first-line tenofovir + emtricitabine + efavirenz for patients with HIV
Cochrane Systematic Reviews, 18-Apr-2012
The current recommended antiretroviral treatment is a highly active antiretroviral therapy (HAART). Although HAART has been associated with improved clinical response to treatment, issues of adherence and viral resistance are major challenges limiting its - Effectiveness and safety of procalcitonin evaluation for reducing mortality in adults with sepsis, severe sepsis or septic shock
Cochrane Systematic Reviews, 18-Jan-2017
Serum procalcitonin (PCT) evaluation has been proposed for early diagnosis and accurate staging and to guide decisions regarding patients with sepsis, severe sepsis and septic shock, with possible reduction in mortality. - Effectiveness of brief alcohol interventions in primary care populations
Cochrane Systematic Reviews, 24-Feb-2018
Excessive drinking is a significant cause of mortality, morbidity and social problems in many countries. Brief interventions aim to reduce alcohol consumption and related harm in hazardous and harmful drinkers who are not actively seeking help for alcohol - Effectiveness of different nursing handover styles for ensuring continuity of information in hospitalised patients
Cochrane Systematic Reviews, 24-Jun-2014
An accurate handover of clinical information is of great importance to continuity and safety of care. If clinically relevant information is not shared accurately and in a timely manner it may lead to adverse events, delays in treatment and diagnosis, inap - Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent)
Cochrane Systematic Reviews, 17-Jul-2018
Granulosa cell tumour is a rare gynaecological tumour of the ovary with recurrences many years after initial diagnosis and treatment. Evidence-based management of granulosa cell tumour of the ovary is limited, and treatment has not been standardised. Surg - Effectiveness of intermediate care in nursing‐led in‐patient units
Cochrane Systematic Reviews, 18-Apr-2007
The Nursing led inpatient Unit (NLU) is one of a range of services that have been considered in order to manage more successfully the transition between hospital and home for patients with extended recovery times. This is an update of an earlier review pu - Effectiveness of organisational infrastructures to promote evidence‐based nursing practice
Cochrane Systematic Reviews, 15-Feb-2012
Nurses and midwives form the bulk of the clinical health workforce and play a central role in all health service delivery. There is potential to improve health care quality if nurses routinely use the best available evidence in their clinical practice. Si - Effectiveness of posterior decompression techniques compared with conventional laminectomy for lumbar stenosis
Cochrane Systematic Reviews, 13-Feb-2015
The gold standard treatment for symptomatic lumbar stenosis refractory to conservative management is a facet-preserving laminectomy. New techniques of posterior decompression have been developed to preserve spinal integrity and to minimise tissue damage b - Effectiveness of provision of animal‐source foods for supporting optimal growth and development in children 6 to 59 months of age
Cochrane Systematic Reviews, 19-Feb-2019
Adequate nutrients early in life promote cognitive development and are critical for proper growth and functioning. The effect of individual nutrients consumed through food is often not the same as consuming the same nutrients in supplementary form due to - Effectiveness of psychosocial interventions for reducing parental substance misuse
Cochrane Systematic Reviews, 16-Mar-2021
Parental substance use is a substantial public health and safeguarding concern. There have been a number of trials of interventions relating to substance-using parents that have sought to address this risk factor, with potential outcomes for parent and ch - Effectiveness of staffing models in residential, subacute, extended aged care settings on patient and staff outcomes
Cochrane Systematic Reviews, 11-May-2011
A key concern for managers and nurse administrators of healthcare settings is staffing. Determining and maintaining an appropriate level and mix of staff is especially problematic for those working in the long-term aged-care sector, where resident needs a - Effectiveness of the Valsalva Manoeuvre for reversion of supraventricular tachycardia
Cochrane Systematic Reviews, 18-Feb-2015
People with the cardiac arrhythmia supraventricular tachycardia (SVT) frequently present to clinicians in the prehospital and emergency medicine settings. Restoring sinus rhythm by terminating the SVT involves increasing the refractoriness of atrioventric - Effectiveness of tranexamic acid in reducing blood loss during cytoreductive surgery for advanced ovarian cancer
Cochrane Systematic Reviews, 23-Jan-2016
Ovarian cancer is the third most common gynaecological cancer worldwide, with an age-standardised incidence rate of 6.1 per 10,000 women. Standard therapy for advanced epithelial ovarian cancer (EOC) includes a combination of cytoreductive surgery and pla - Effectiveness of vocational rehabilitation intervention on the return to work and employment of persons with multiple sclerosis
Cochrane Systematic Reviews, 21-Jan-2009
Multiple sclerosis is a neurological disease that frequently affects adults of working age, resulting in a range of physical, cognitive and psychosocial deficits that impact on workforce participation. Although, the literature supports vocational rehabili - Effects and safety of periconceptional oral folate supplementation for preventing birth defects
Cochrane Systematic Reviews, 14-Dec-2015
It has been reported that neural tube defects (NTD) can be prevented with periconceptional folic acid supplementation. The effects of different doses, forms and schemes of folate supplementation for the prevention of other birth defects and maternal and i - Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease
Cochrane Systematic Reviews, 24-Feb-2022
Cardiovascular diseases (CVD) are a major cause of disability and the leading cause of death worldwide. To reduce mortality and morbidity, prevention strategies such as following an optimal diet are crucial. In recent years, low-gluten and gluten-free die - Effects of all‐trans retinoic acid (ATRA) in addition to chemotherapy for adults with acute myeloid leukaemia (AML) (non‐acute promyelocytic leukaemia (non‐APL))
Cochrane Systematic Reviews, 6-Aug-2018
Acute myeloid leukaemia (AML) is the most common acute leukaemia affecting adults. Most patients diagnosed with AML are at advanced age and present with co-morbidities, so that intensive therapy such as stem cell transplantation (SCT) is impossible to pro - Effects of changes in the pre‐licensure education of health workers on health‐worker supply
Cochrane Systematic Reviews, 15-Apr-2009
The current and projected crisis because of a shortage of health workers in low and middle-income countries (LMICs) requires that effective strategies for expanding the numbers of health workers are quickly identified in order to inform action by policyma
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