- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic obstructive pulmonary disease (COPD) is a common and progressive disease characterised by chronic cough, airflow limitation and recurrent exacerbations. Since COPD exacerbations are linked to rising mortality and reduced quality of life, the condi - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cerebral palsy is the most common physical disability in childhood. Mechanically assisted walking training can be provided with or without body weight support to enable children with cerebral palsy to perform repetitive practice of complex gait cycles. It - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Approximately 2.5% of all hospitalisations in people with cirrhosis are for spontaneous bacterial peritonitis (SBP). Antibiotics, in addition to supportive treatment (fluid and electrolyte balance, treatment of shock), form the mainstay treatments of SBP. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Approximately 20% of people with cirrhosis develop ascites. Several different treatments are available; including, among others, paracentesis plus fluid replacement, transjugular intrahepatic portosystemic shunts, aldosterone antagonists, and loop diureti - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Older patients with multiple health problems (multi-morbidity) value being involved in decision-making about their health care. However, they are less frequently involved than younger patients. To maximise quality of life, day-to-day function, and patient - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Approximately 2.5% of all hospitalisations in people with liver cirrhosis are for spontaneous bacterial peritonitis. Spontaneous bacterial peritonitis is associated with significant short-term mortality; therefore, it is important to prevent spontaneous b - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pruritus is a sensation that leads to the desire to scratch; its origin is unknown in 8% to 15% of affected patients. The prevalence of chronic pruritus of unknown origin (CPUO) in individuals with generalised pruritus ranges from 3.6% to 44.5%, with high - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Continuous spike-wave during slow wave sleep syndrome (CSWS) and Landau-Kleffner syndrome (LKS) are two epileptic encephalopathies that present with neurocognitive regression, aphasia, and clinical seizures, typically presenting in children around five ye - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Symptomatic patent ductus arteriosus (PDA) is associated with mortality and morbidity in preterm infants. In these infants, prophylactic use of indomethacin, a non-selective cyclooxygenase inhibitor, has demonstrated short-term clinical benefits. The effe - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
According to the Global Burden of Disease Study 2015, lower respiratory tract infection is the leading cause of infectious disease death, and the fifth most common cause of death overall. Vitamin C has a role in modulating resistance to infectious agents, - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Intimate partner abuse (including coercive control, physical, sexual, economic, emotional and economic abuse) is common worldwide. Advocacy may help women who are in, or have left, an abusive intimate relationship, to stop or reduce repeat victimisation a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Clinical practice guidelines suggest that magnetic resonance imaging (MRI) of the brain should be performed at certain time points or intervals distant from diagnosis (interval or surveillance imaging) of cerebral glioma, to monitor or follow up the disea - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Gender dysphoria is described as a mismatch between an individual's experienced or expressed gender and their assigned gender, based on primary or secondary sexual characteristics. Gender dysphoria can be associated with clinically significant psychologic - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Recently conducted randomised controlled trials (RCTs) suggest that late commencement of parenteral nutrition (PN) may have clinical benefits in critically ill adults and children. However, there is currently limited evidence regarding the optimal timing - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, in which the pathogenesis is believed to be partly influenced by the gut microbiome. Probiotics can be used to manipulate the microbiome and have therefore been conside - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Compared with people without cancer, people with cancer who receive anticoagulant treatment for venous thromboembolism (VTE) are more likely to develop recurrent VTE. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cancer increases the risk of thromboembolic events, especially in people receiving anticoagulation treatments. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Laparoscopic cholecystectomy is used to manage symptomatic gallstones. There is considerable controversy regarding whether it should be done as day-surgery or as an overnight stay surgery with regards to patient safety. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
In many countries of the industrialised world second generation ('atypical') antipsychotics have become the first line drug treatment for people with schizophrenia. The question as to whether, and if so how much, the effects of the various new generation - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Granulocyte-colony stimulating factor (G-CSF) increases the release of neutrophil endothelial progenitor cells from the bone marrow and improves neutrophil functions, which are often impaired in people with diabetes.
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