- Early skin‐to‐skin contact for mothers and their healthy newborn infants
Cochrane Systematic Reviews, 25-Nov-2016
Mother-infant separation post birth is common. In standard hospital care, newborn infants are held wrapped or dressed in their mother’s arms, placed in open cribs or under radiant warmers. Skin-to-skin contact (SSC) begins ideally at birth and should last - Early supported discharge services for people with acute stroke
Cochrane Systematic Reviews, 13-Jul-2017
People with stroke conventionally receive a substantial part of their rehabilitation in hospital. Services have now been developed that offer people in hospital an early discharge with rehabilitation at home (early supported discharge: ESD). - Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome
Cochrane Systematic Reviews, 17-Oct-2007
Both prophylactic and early surfactant replacement therapy reduce mortality and pulmonary complications in ventilated infants with respiratory distress syndrome (RDS) compared with later selective surfactant administration. However, continued post-surfact - Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants
Cochrane Systematic Reviews, 10-Dec-2020
Patent ductus arteriosus (PDA) is associated with significant morbidity and mortality in preterm infants. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to prevent or treat a PDA. There are concerns regarding adverse effects of NSAIDs in preterm i - Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants
Cochrane Systematic Reviews, 25-Feb-2013
The introduction of enteral feeds for very preterm (< 32 weeks) or very low birth weight (< 1500 grams) infants is often delayed due to concern that early introduction may not be tolerated and may increase the risk of necrotising enterocolitis. However, p - Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Cochrane Systematic Reviews, 12-Dec-2012
Systemic corticosteroid therapy is central to the management of acute asthma. The use of inhaled corticosteroids (ICS) may also be beneficial in this setting. - Early versus deferred standard androgen suppression therapy for advanced hormone‐sensitive prostate cancer
Cochrane Systematic Reviews, 11-Jun-2019
Standard androgen suppression therapy (AST) using surgical or medical castration is considered a mainstay of advanced hormone-sensitive prostate cancer treatment. AST can be initiated early when disease is asymptomatic or deferred when patients suffer sym - Early versus deferred treatment for early stage multiple myeloma
Cochrane Systematic Reviews, 20-Jan-2003
Early stage multiple myeloma (MM) represents about 20% of MM. Most of the patients are asymptomatic. Thus, it is far less dramatic than advanced disease and may require different treatment strategies. For these patients, it is not clear whether it is bett - Early versus delayed antiretroviral treatment in HIV‐positive people with cryptococcal meningitis
Cochrane Systematic Reviews, 24-Jul-2018
There remains uncertainty about the optimum timing of antiretroviral therapy (ART) initiation in HIV-positive people with cryptococcal meningitis. This uncertainty is the result of conflicting data on the mortality risk and occurrence of immune reconstitu - Early versus delayed appendicectomy for appendiceal phlegmon or abscess
Cochrane Systematic Reviews, 2-Jun-2017
Appendiceal phlegmon and abscess account for 2% to 10% of acute appendicitis. People with appendiceal phlegmon or abscess usually need an appendicectomy to relieve their symptoms and avoid complications. The timing of appendicectomy for appendiceal phlegm - Early versus delayed continuous positive airway pressure (CPAP) for respiratory distress in preterm infants
Cochrane Systematic Reviews, 15-Oct-2020
The application of continuous positive airway pressure (CPAP) has been shown to have some benefits in the treatment of preterm infants with respiratory distress. CPAP has the potential to reduce lung damage, particularly if applied early before atelectasi - Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds
Cochrane Systematic Reviews, 3-Sep-2015
Most surgical procedures involve a cut in the skin that allows the surgeon to gain access to the deeper tissues or organs. Most surgical wounds are closed fully at the end of the procedure (primary closure). The surgeon covers the closed surgical wound wi - Early versus delayed enteral nutrition support for burn injuries
Cochrane Systematic Reviews, 19-Oct-2008
A burn injury increases the body's metabolic demands, and therefore nutritional requirements. Provision of an adequate supply of nutrients is believed to lower the incidence of metabolic abnormalities, thus reducing septic morbidity, improving survival ra - Early versus delayed erythropoietin for the anaemia of end‐stage kidney disease
Cochrane Systematic Reviews, 16-Dec-2015
Anaemia is a common complication in people with chronic kidney disease (CKD) and mainly develops as a consequence of relative erythropoietin (EPO) deficiency. Anaemia develops early in the course of disease and peaks among people with end-stage kidney dis - Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
Cochrane Systematic Reviews, 28-Aug-2013
Gallstones and alcohol account for more than 80% of acute pancreatitis. Cholecystectomy is the definitive treatment for gallstones. Laparoscopic cholecystectomy is the preferred route for performing cholecystectomy. The timing of laparoscopic cholecystect - Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis
Cochrane Systematic Reviews, 30-Jun-2013
Gallstones are present in about 10% to 15% of the adult western population. Between 1% and 4% of these adults become symptomatic in a year (the majority due to biliary colic but a significant proportion due to acute cholecystitis). Laparoscopic cholecyste - Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic
Cochrane Systematic Reviews, 26-Jun-2013
Uncomplicated biliary colic is one of the commonest indications for laparoscopic cholecystectomy. Laparoscopic cholecystectomy involves several months of waiting if performed electively. However, people can develop life-threatening complications during th - Early versus delayed mobilisation for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 9-Apr-2013
Rebleeding is an important cause of death and disability in patients with aneurysmal subarachnoid haemorrhage (SAH). In order to prevent rebleeding, the preferred strategy is aneurysm ablation (removal) as early as possible. However, in clinical practice - Early versus delayed oral fluids and food for reducing complications after major abdominal gynaecologic surgery
Cochrane Systematic Reviews, 12-Dec-2014
This is an updated version of the original Cochrane review published in 2007. Traditionally, after major abdominal gynaecologic surgery postoperative oral intake is withheld until the return of bowel function. There has been concern that early oral intake - Early versus delayed post‐operative bathing or showering to prevent wound complications
Cochrane Systematic Reviews, 23-Jul-2015
Many people undergo surgical operations during their life-time, which result in surgical wounds. After an operation the incision is closed using stiches, staples, steri-strips or an adhesive glue. Usually, towards the end of the surgical procedure and bef
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