- Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic
Cochrane Systematic Reviews, 26-Jun-2013
Uncomplicated biliary colic is one of the commonest indications for laparoscopic cholecystectomy. Laparoscopic cholecystectomy involves several months of waiting if performed electively. However, people can develop life-threatening complications during th - Early versus delayed mobilisation for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 9-Apr-2013
Rebleeding is an important cause of death and disability in patients with aneurysmal subarachnoid haemorrhage (SAH). In order to prevent rebleeding, the preferred strategy is aneurysm ablation (removal) as early as possible. However, in clinical practice - Early versus delayed oral fluids and food for reducing complications after major abdominal gynaecologic surgery
Cochrane Systematic Reviews, 12-Dec-2014
This is an updated version of the original Cochrane review published in 2007. Traditionally, after major abdominal gynaecologic surgery postoperative oral intake is withheld until the return of bowel function. There has been concern that early oral intake - Early versus delayed post‐operative bathing or showering to prevent wound complications
Cochrane Systematic Reviews, 10-Jul-2015
Many people undergo surgical operations during their life-time, which result in surgical wounds. After an operation the incision is closed using stiches, staples, steri-strips or an adhesive glue. Usually, towards the end of the surgical procedure and bef - Early versus delayed postoperative radiotherapy for treatment of low‐grade gliomas
Cochrane Systematic Reviews, 16-Jan-2020
This is an update of the review originally published in 2011 and first updated in 2015. - Early versus Delayed Refeeding for Children with Acute Diarrhoea
Cochrane Systematic Reviews, 14-Jun-2011
Acute diarrhoea is one of the principal causes of morbidity and mortality among children in low-income countries. The cornerstone of treatment is oral rehydration therapy and dietary management. However, there is a lack of data and studies on both the t - Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome
Cochrane Systematic Reviews, 15-Oct-2012
Clinical trials have confirmed that surfactant therapy is effective in improving the immediate need for respiratory support and the clinical outcome of premature newborns. Trials have studied a wide variety of surfactant preparations used either to preven - Early versus late administration of amino acids in preterm infants receiving parenteral nutrition
Cochrane Systematic Reviews, 23-Jul-2013
Observational studies in preterm newborns suggest that delay in administering amino acids could result in a protein catabolic state and could impact on growth and development. - Early versus late antiepileptic drug withdrawal for people with epilepsy in remission
Cochrane Systematic Reviews, 29-Apr-2015
Epilepsy is a chronic neurological disorder which affects millions of people around the world. Antiepileptic drugs (AED) are the main interventions used to prevent seizures and control epilepsy. Although effective in most cases, AEDs are related to long-t - Early versus late chest radiotherapy in patients with limited-stage small cell lung cancer
Cochrane Systematic Reviews, 8-Nov-2010
This is an update of the original review published in Issue 1, 2005. It is standard clinical practice to combine chemotherapy and chest radiotherapy in treating patients with limited-stage small cell lung cancer. However, the best way to integrate both mo - Early versus late discontinuation of oxygen in preterm or low birth weight infants
Cochrane Systematic Reviews, 12-Aug-2009
It has been hypothesized that the duration of supplemental oxygen administration, independent of the oxygen concentration, gestational age and/or birth weight, is influential in the development of severe retinopathy of prematurity (ROP). Concern regarding - Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Cochrane Systematic Reviews, 27-Jan-2020
Low plasma levels of erythropoietin (EPO) in preterm infants provide a rationale for the use of EPO to prevent or treat anaemia. - Early versus late initiation of epidural analgesia for labour
Cochrane Systematic Reviews, 1-Oct-2014
Pain during childbirth is arguably the most severe pain some women may experience in their lifetime. Epidural analgesia is an effective form of pain relief during labour. Many women have concerns regarding its safety. Furthermore, epidural services and an - Early versus late parenteral nutrition for critically ill term and late preterm infants
Cochrane Systematic Reviews, 6-Apr-2020
Recently conducted randomised controlled trials (RCTs) suggest that late commencement of parenteral nutrition (PN) may have clinical benefits in critically ill adults and children. However, there is currently limited evidence regarding the optimal timing - Early versus late pre‐intensive care unit admission broad spectrum antibiotics for severe sepsis in adults
Cochrane Systematic Reviews, 14-Dec-2018
Severe sepsis and septic shock have recently emerged as particularly acute and lethal challenges amongst critically ill patients presenting to the emergency department (ED). There are no existing data on the current practices of management of patients wit - Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia
Cochrane Systematic Reviews, 10-Aug-2015
The laryngeal mask airway (LMA) is a safe and effective modality to maintain the airway for general anaesthesia during surgical procedures. The LMA is removed at the end of surgery and anaesthesia, when the patient maintains an adequate respiratory rate a - Early versus late tracheostomy for critically ill patients
Cochrane Systematic Reviews, 14-Dec-2018
Long-term mechanical ventilation is the most common situation for which tracheostomy is indicated for patients in intensive care units (ICUs). 'Early' and 'late' tracheostomies are two categories of the timing of tracheostomy. Evidence on the advantages a - Early versus late ureteric stent removal after kidney transplantation
Cochrane Systematic Reviews, 18-Jan-2018
Kidney transplantation is the treatment of choice for patients with end-stage kidney disease. In a previous review we concluded that the routine use of ureteric stents in kidney transplantation reduces the incidence of major urological complications (MUC) - Early volume expansion for prevention of morbidity and mortality in very preterm infants
Cochrane Systematic Reviews, 12-May-2009
Reduced perfusion of organs such as the brain, heart, kidneys and the gastrointestinal tract may lead to acute dysfunction and be associated with permanent injury. Various strategies have been used to provide cardiovascular support to preterm infants incl - Early volume expansion versus inotrope for prevention of morbidity and mortality in very preterm infants
Cochrane Systematic Reviews, 6-Nov-2008
Reduced perfusion of organs such as the brain, heart, kidneys and the gastrointestinal tract may lead to acute dysfunction and be associated with permanent injury. Various strategies have been used to provide cardiovascular support to preterm infants incl
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