- Antibiotic prophylaxis regimens and drugs for cesarean section
Cochrane Systematic Reviews, 6-Dec-2011
Prophylactic antibiotics for cesarean section have been shown to reduce the incidence of maternal postoperative infectious morbidity. Many different antibiotic regimens have been reported to be effective. - Antibiotic regimens for management of intraamniotic infection
Cochrane Systematic Reviews, 19-Dec-2014
Intraamniotic infection is associated with maternal morbidity and neonatal sepsis, pneumonia and death. Although antibiotic treatment is accepted as the standard of care, few studies have been conducted to examine the effectiveness of different antibiotic - Antibiotic regimens for management of intra-amniotic infection
Cochrane Systematic Reviews, 19-Dec-2014
Chorioamnionitis is a common infection that affects both mother and infant. Infant complications associated with chorioamnionitis include early neonatal sepsis, pneumonia, and meningitis. Chorioamnionitis can also result in maternal morbidity such as pelv - Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults
Cochrane Systematic Reviews, 26-Mar-2012
Secondary peritonitis is associated with a high mortality rate and if not treated successfully leads to development of abscesses, severe sepsis and multi-organ failure. Source control and adjunctive antibiotics are the mainstay of treatment. However, no c - Antibiotic regimens for suspected early neonatal sepsis
Cochrane Systematic Reviews, 29-Oct-2008
Early acquired infection may cause severe illness or death in the neonatal period. Prompt treatment with antibiotics has shown to reduce mortality. It is not clear which antibiotic regimen is suitable for treatment of presumed early neonatal sepsis. - Antibiotic regimens for suspected late onset sepsis in newborn infants
Cochrane Systematic Reviews, 17-Apr-2012
Late onset neonatal sepsis (systemic infection after 48 hours of age) continues to be a significant cause of morbidity and mortality. Early treatment with antibiotics is essential as infants can deteriorate rapidly. It is not clear which antibiotic regime - Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
Cochrane Systematic Reviews, 9-Jul-2012
Although the exact aetiology of necrotising enterocolitis (NEC) remains unknown, research suggests that it is multifactorial; suspected pathophysiological mechanisms include immaturity, intestinal ischaemia, disruption of intestinal mucosal integrity, for - Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds
Cochrane Systematic Reviews, 15-Nov-2013
Non surgical wounds include chronic ulcers (pressure or decubitus ulcers, venous ulcers, diabetic ulcers, ischaemic ulcers), burns and traumatic wounds. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonisation (i.e. presence of MR - Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Cochrane Systematic Reviews, 6-Aug-2013
Methicillin-resistant Staphylococcus aureus (MRSA) infection after surgery is usually rare, but incidence can be up to 33% in certain types of surgery. Postoperative MRSA infection can occur as surgical site infections (SSI), chest infections, or bloodstr - Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults
Cochrane Systematic Reviews, 3-Mar-2017
Clostridium difficile (C. difficile) is recognized as a frequent cause of antibiotic-associated diarrhoea and colitis. This review is an update of a previously published Cochrane review. - Antibiotic treatment for newborns with congenital syphilis
Cochrane Systematic Reviews, 12-Feb-2019
Congenital syphilis continues to be a substantial public health problem in many parts of the world. Since the first use of penicillin for the treatment of syphilis in 1943, which was a notable early success, it has remained the preferred and standard trea - Antibiotic treatment for the sexual partners of women with bacterial vaginosis
Cochrane Systematic Reviews, 27-Sep-2016
Bacterial vaginosis (BV) is an infection that has a prevalence between 10% to 50% worlwide. BV results in an imbalance of the normal vaginal flora. Microorganisms associated with BV have been isolated from the normal flora of the male genital tract, and t - Antibiotics / anti-inflammatories for reducing acute inflammatory episodes in lymphoedema of the limbs
Cochrane Systematic Reviews, 22-Oct-2008
Lymphoedema is a chronic, progressive condition and one area of debate is the optimum management for infective/inflammatory episodes (AIE's). - Antibiotics and antiseptics for venous leg ulcers
Cochrane Systematic Reviews, 9-Jan-2014
Venous leg ulcers are a type of chronic wound affecting up to 1% of adults in developed countries at some point during their lives. Many of these wounds are colonised by bacteria or show signs of clinical infection. The presence of infection may delay ulc - Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants
Cochrane Systematic Reviews, 20-Feb-2018
Late-onset sepsis is associated with increased rates of mortality and morbidity in newborn infants, in addition to poorer long-term developmental outcomes and increased length of stay and hospital costs. Central line-associated blood stream infection (CLA - Antibiotics for acute maxillary sinusitis in adults
Cochrane Systematic Reviews, 15-Oct-2015
Sinusitis is one of the most common diagnoses among adults in ambulatory care, accounting for 15% to 21% of all adult outpatient antibiotic prescriptions. However, the role of antibiotics for sinusitis is controversial. - Antibiotics for acute pyelonephritis in children
Cochrane Systematic Reviews, 25-Jul-2014
Urinary tract infection (UTI) is one of the most common bacterial infections in infants. The most severe form of UTI is acute pyelonephritis, which results in significant acute morbidity and may cause permanent kidney damage. There remains uncertainty reg - Antibiotics for asymptomatic bacteriuria
Cochrane Systematic Reviews, 29-Jun-2015
Asymptomatic bacteriuria is commonly detected in women aged up to 60 years, patients with diabetes, and the elderly. The benefit of antibiotic treatment for this condition is controversial. - Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children
Cochrane Systematic Reviews, 4-Jan-2015
Mycoplasma pneumoniae (M. pneumoniae) is widely recognised as an important cause of community-acquired lower respiratory tract infection (LRTI) in children. Pulmonary manifestations are typically tracheobronchitis or pneumonia but M. pneumoniae is also i - Antibiotics for exacerbations of asthma
Cochrane Systematic Reviews, 21-Jun-2018
Asthma is a chronic respiratory condition that affects over 300 million adults and children worldwide. It is characterised by wheeze, cough, chest tightness, and shortness of breath. Symptoms typically are intermittent and may worsen over a short time, le
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