- Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation
Cochrane Systematic Reviews, 26-Oct-2015
Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, som - Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
Cochrane Systematic Reviews, 10-Apr-2019
Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of craving and withdrawal symptoms. Although there is clear evidence that NRT used - Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 5-Mar-2018
Current guidelines recommend that patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) should be treated with systemic corticosteroid for seven to 14 days. Intermittent systemic corticosteroid use is cumulatively associated wi - Different functional treatment strategies for acute lateral ankle ligament injuries in adults
Cochrane Systematic Reviews, 28-Feb-2013
Acute lateral ankle ligament ruptures are common problems in present health care. Early mobilisation and functional treatment are advocated as a preferable treatment strategy. However, functional treatment comprises a broad spectrum of treatment strategie - Different infusion durations for preventing platinum‐induced hearing loss in children with cancer
Cochrane Systematic Reviews, 20-Jan-2020
Platinum-based therapy, including cisplatin, carboplatin or oxaliplatin, or a combination of these, is used to treat a variety of paediatric malignancies. Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototox - Different insulin types and regimens for pregnant women with pre‐existing diabetes
Cochrane Systematic Reviews, 2-Feb-2017
Insulin requirements may change during pregnancy, and the optimal treatment for pre-existing diabetes is unclear. There are several insulin regimens (e.g. via syringe, pen) and types of insulin (e.g. fast-acting insulin, human insulin). - Different intensities of glycaemic control for pregnant women with pre‐existing diabetes
Cochrane Systematic Reviews, 27-Apr-2016
The optimal glycaemic control target in pregnant women with pre-existing diabetes is unclear, although there is a clear link between high glucose concentrations and adverse birth outcomes. - Different intensities of glycaemic control for women with gestational diabetes mellitus
Cochrane Systematic Reviews, 5-Apr-2016
Gestational diabetes mellitus (GDM) has major short- and long-term implications for both the mother and her baby. GDM is defined as a carbohydrate intolerance resulting in hyperglycaemia or any degree of glucose intolerance with onset or first recognition - Different lasers and techniques for proliferative diabetic retinopathy
Cochrane Systematic Reviews, 26-Mar-2018
Diabetic retinopathy (DR) is a chronic progressive disease of the retinal microvasculature associated with prolonged hyperglycaemia. Proliferative DR (PDR) is a sight-threatening complication of DR and is characterised by the development of abnormal new v - Different magnesium sulphate regimens for neuroprotection of the fetus for women at risk of preterm birth
Cochrane Systematic Reviews, 11-Jan-2012
The effectiveness of antenatal magnesium sulphate for neuroprotection of the fetus, infant, and child prior to very preterm birth, when given to women considered at risk of preterm birth, has been established. There is currently no consensus as to the reg - Different methods and settings for glucose monitoring for gestational diabetes during pregnancy
Cochrane Systematic Reviews, 24-Oct-2017
Incidence of gestational diabetes mellitus (GDM) is increasing worldwide. Blood glucose monitoring plays a crucial part in maintaining glycaemic control in women with GDM and is generally recommended by healthcare professionals. There are several differen - Different methods of external fixation for treating distal radial fractures in adults
Cochrane Systematic Reviews, 10-Aug-2008
Fracture of the distal radius is a common injury. A surgical treatment is external fixation, where metal pins inserted into bone on either side of the fracture are then fixed to an external frame. - Different oral corticosteroid regimens for acute asthma
Cochrane Systematic Reviews, 11-May-2016
Asthma is a common long-term breathing condition that affects approximately 300 million people worldwide. People with asthma may experience short-term worsening of their asthma symptoms; these episodes are often known as ‘exacerbations’, ‘flare-ups’, ‘att - Different powered toothbrushes for plaque control and gingival health
Cochrane Systematic Reviews,
Powered brushes were first introduced commercially in the 1960s. A recent systematic review suggested the superiority of certain modes of powered over manual toothbrushing for plaque and gingivitis reduction. That review did not allow for direct compariso - Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression
Cochrane Systematic Reviews, 20-Mar-2017
Depression is a common mental disorder. It affects millions of people worldwide and is considered by the World Health Organization (WHO) to be one of the leading causes of disability. Electroconvulsive therapy (ECT) is a well-established treatment for sev - Different strategies for diagnosing gestational diabetes to improve maternal and infant health
Cochrane Systematic Reviews, 15-Aug-2017
Gestational diabetes mellitus (GDM) is carbohydrate intolerance resulting in hyperglycaemia with onset or first recognition during pregnancy. If untreated, perinatal morbidity and mortality may be increased. Accurate diagnosis allows appropriate treatment - Different treatment regimens of magnesium sulphate for tocolysis in women in preterm labour
Cochrane Systematic Reviews, 11-Dec-2015
Magnesium sulphate has been used to inhibit preterm labour to prevent preterm birth. There is no consensus as to the safety profile of different treatment regimens with respect to dose, duration, route and timing of administration. - Different types of dietary advice for women with gestational diabetes mellitus
Cochrane Systematic Reviews, 18-Apr-2017
Dietary advice is the main strategy for managing gestational diabetes mellitus (GDM). It remains unclear what type of advice is best. - Different types of implants for reconstructive breast surgery
Cochrane Systematic Reviews, 5-May-2016
Breast cancer is the most common cancer in women worldwide, and is a leading cause of cancer death among women. Prophylactic or curative mastectomy is often followed by breast reconstruction for which there are several surgical approaches that use breast - Different types of intermittent pneumatic compression devices for preventing venous thromboembolism in patients after total hip replacement
Cochrane Systematic Reviews, 18-Dec-2014
Total hip replacement (THR) is an effective treatment for reducing pain and improving function and quality of life in patients with hip disorders. While this operation is very successful, deep vein thrombosis (DVT) and pulmonary embolism (PE) are signific
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