- Deep versus shallow suction of endotracheal tubes in ventilated neonates and young infants
Cochrane Systematic Reviews, 6-Jul-2011
Mechanical ventilation is commonly used in Neonatal Intensive Care Units to assist breathing in a variety of conditions. Mechanical ventilation is achieved through the placement of an endotracheal tube (ETT) which is left in-situ. The ETT is suctioned to - De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
Cochrane Systematic Reviews, 20-Dec-2018
Mortality rates among patients with sepsis, severe sepsis or septic shock are highly variable throughout different regions or services and can be upwards of 50%. Empirical broad-spectrum antimicrobial treatment is aimed at achieving adequate antimicrobial - De‐escalation techniques for managing non‐psychosis induced aggression in adults
Cochrane Systematic Reviews, 18-Jul-2018
Aggression occurs frequently within health and social care settings. It can result in injury to patients and staff and can adversely affect staff performance and well-being. De-escalation is a widely used and recommended intervention for managing aggressi - De‐escalation techniques for psychosis‐induced aggression or agitation
Cochrane Systematic Reviews, 3-Apr-2017
Aggression is a disposition, a willingness to inflict harm, regardless of whether this is behaviourally or verbally expressed and regardless of whether physical harm is sustained. - De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma
Cochrane Systematic Reviews, 5-Feb-2014
Human papillomavirus-associated oropharyngeal squamous cell carcinomas are a distinct subgroup of tumours that may have a better prognosis than traditional tobacco/alcohol-related disease. Iatrogenic complications, associated with conventional practice, a - Deferasirox for managing iron overload in people with myelodysplastic syndrome
Cochrane Systematic Reviews, 28-Oct-2014
The myelodysplastic syndrome (MDS) comprises a diverse group of haematopoietic stem cell disorders. Due to symptomatic anaemia, most people with MDS require supportive therapy including repeated red blood cell (RBC) transfusions. In combination with incre - Deferasirox for managing iron overload in people with thalassaemia
Cochrane Systematic Reviews, 15-Aug-2017
Thalassaemia is a hereditary anaemia due to ineffective erythropoiesis. In particular, people with thalassaemia major develop secondary iron overload resulting from regular red blood cell transfusions. Iron chelation therapy is needed to prevent long-term - Deferasirox for managing transfusional iron overload in people with sickle cell disease
Cochrane Systematic Reviews, 4-Jun-2014
Sickle cell disease (SCD) is a group of genetic haemoglobin disorders, that occurs in about 2.2 per 1000 births worldwide. Increasingly, some people with SCD develop secondary iron overload due to occasional red blood cell transfusions or are on long-term - Deflation of gastric band balloon in pregnancy for improving outcomes
Cochrane Systematic Reviews, 19-Mar-2013
In line with the rise in the prevalence of obesity, an increasing number of women of childbearing age are undergoing laparoscopic adjustable gastric banding (LAGB), resulting in an increasing number of pregnancies with a band in place. Currently, there is - Degarelix for treating advanced hormone‐sensitive prostate cancer
Cochrane Systematic Reviews, 5-Aug-2021
Degarelix is a gonadotropin-releasing hormone antagonist that leads to medical castration used to treat men with advanced or metastatic prostate cancer, or both. It is unclear how its effects compare to standard androgen suppression therapy. - Dehumidifiers for chronic asthma
Cochrane Systematic Reviews, 13-Jun-2013
Humidity control measures in the home environment of patients with asthma have been recommended, since a warm humid environment favours the growth of house dust mites. However, there is no consensus about the usefulness of these measures. - Dehydroepiandrosterone (DHEA) supplementation for cognitive function
Cochrane Systematic Reviews, 6-Nov-2008
In view of the theoretical rationale for beneficial effects of DHEA and DHEAS on cognitive function in ageing and dementia, we have undertaken a thorough investigation of well-conducted studies in this area. This will provide a basis for confirmation of a - Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people
Cochrane Systematic Reviews, 18-Dec-2008
In view of the theoretical possibility of beneficial effects of DHEA retarding age-associated deterioration in cognitive function, we have reviewed studies in this area. - Dehydroepiandrosterone for systemic lupus erythematosus
Cochrane Systematic Reviews, 17-Oct-2007
Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem autoimmune condition. Dehydroepiandrosterone (DHEA) is a naturally occurring inactive steroid which may possess disease activity modifying properties as well as the ability to reduc - Dehydroepiandrosterone for women in the peri- or postmenopausal phase
Cochrane Systematic Reviews, 19-Jan-2015
During menopause a decreasing ovarian follicular response generally causes a fluctuation and eventual decrease in estrogen levels. This can lead to the development of various perimenopausal and postmenopausal symptoms (for example hot flushes, night sweat - De‐intensified adjuvant (chemo)radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV‐positive oropharyngeal carcinoma
Cochrane Systematic Reviews, 14-Dec-2018
More than 400,000 cases of oropharyngeal squamous cell cancer (OPSCC) are diagnosed every year worldwide and this is rising. Much of the increase has been attributed to human papillomavirus (HPV). HPV-positive OPSCC patients are often younger and have sig - Delayed antibiotic prescriptions for respiratory infections
Cochrane Systematic Reviews, 7-Sep-2017
Concerns exist regarding antibiotic prescribing for respiratory tract infections (RTIs) owing to adverse reactions, cost, and antibacterial resistance. One proposed strategy to reduce antibiotic prescribing is to provide prescriptions, but to advise delay - Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants
Cochrane Systematic Reviews, 20-Jan-2022
Enteral feeding for very preterm or very low birth weight (VLBW) infants is often delayed for several days after birth due to concern that early introduction of feeding may not be tolerated and may increase the risk of necrotising enterocolitis. Concerns - Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)
Cochrane Systematic Reviews, 12-Oct-2016
Functional endoscopic sinus surgery (FESS) is a minimally invasive technique that is used to treat chronic sinusitis. Small bleeding areas can reduce operative visibility and result in destruction of surrounding structures. Deliberate hypotension (lowerin - Delivery arrangements for health systems in low‐income countries: an overview of systematic reviews
Cochrane Systematic Reviews, 13-Sep-2017
Delivery arrangements include changes in who receives care and when, who provides care, the working conditions of those who provide care, coordination of care amongst different providers, where care is provided, the use of information and communication te
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