- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury
Cochrane Systematic Reviews, 30-Dec-2019
High intracranial pressure (ICP) is the most frequent cause of death and disability after severe traumatic brain injury (TBI). It is usually treated with general maneuvers (normothermia, sedation, etc.) and a set of first-line therapeutic measures (modera - Decompressive surgery for treating nerve damage in leprosy
Cochrane Systematic Reviews, 9-Nov-2012
Leprosy causes nerve damage which may result in nerve function impairment and disability. Decompressive surgery is used for treating nerve damage, although the effect is uncertain. This is an update of a review first published in 2009 and previously updat - Decompressive surgery of lower limbs for symmetrical diabetic peripheral neuropathy
Cochrane Systematic Reviews, 28-Feb-2011
Symmetrical peripheral neuropathy is a common complication of diabetic neuropathy. No treatments are known to be effective for progressive pain and sensory loss associated with diabetic neuropathy. Alternative effective treatment strategies have been soug - Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
Cochrane Systematic Reviews, 15-Oct-2014
The efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis has not been systematically evaluated. - Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus
Cochrane Systematic Reviews, 10-Jul-2014
Keratoconus is an ectatic (weakening) disease of the cornea, which is the clear surface at the front of the eye. Approximately 10% to 15% of patients diagnosed with keratoconus require corneal transplantation. This may be full-thickness (penetrating) or p - Deep brain and cortical stimulation for epilepsy
Cochrane Systematic Reviews, 12-Jul-2017
Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. Since the 1970s interest has grown in invasive intracranial neurostimulation as a treatment for these patients. Intracranial stimulation incl - Deep brain stimulation for dystonia
Cochrane Systematic Reviews,
Dystonia is a painful and disabling disorder, characterised by painful, involuntary posturing of the affected body region(s). Deep brain stimulation is an intervention typically reserved for severe and drug-refractory cases, although uncertainty exists re - Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis
Cochrane Systematic Reviews, 28-Oct-2014
Deep transverse friction massage, one of several physical therapy interventions suggested for the management of tendinitis pain, was first demonstrated in the 1930s by Dr James Cyriax, a renowned orthopedic surgeon in England. Its goal is to prevent abnor - Deep versus shallow suction of endotracheal tubes in ventilated neonates and young infants
Cochrane Systematic Reviews, 22-May-2013
Mechanical ventilation is commonly used in Neonatal Intensive Care Units to assist breathing in a variety of conditions. Mechanical ventilation is achieved through the placement of an endotracheal tube (ETT) which is left in-situ. The ETT is suctioned to - De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
Cochrane Systematic Reviews, 20-Dec-2018
Mortality rates among patients with sepsis, severe sepsis or septic shock are highly variable throughout different regions or services and can be upwards of 50%. Empirical broad-spectrum antimicrobial treatment is aimed at achieving adequate antimicrobial - De‐escalation techniques for managing non‐psychosis induced aggression in adults
Cochrane Systematic Reviews, 17-Jul-2018
Aggression occurs frequently within health and social care settings. It can result in injury to patients and staff and can adversely affect staff performance and well-being. De-escalation is a widely used and recommended intervention for managing aggressi - De‐escalation techniques for psychosis‐induced aggression or agitation
Cochrane Systematic Reviews, 10-Apr-2017
Aggression is a disposition, a willingness to inflict harm, regardless of whether this is behaviourally or verbally expressed and regardless of whether physical harm is sustained. - De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma
Cochrane Systematic Reviews, 5-Feb-2014
Human papillomavirus-associated oropharyngeal squamous cell carcinomas are a distinct subgroup of tumours that may have a better prognosis than traditional tobacco/alcohol-related disease. Iatrogenic complications, associated with conventional practice, a - Deferasirox for managing iron overload in people with myelodysplastic syndrome
Cochrane Systematic Reviews, 23-Oct-2014
The myelodysplastic syndrome (MDS) comprises a diverse group of haematopoietic stem cell disorders. Due to symptomatic anaemia, most people with MDS require supportive therapy including repeated red blood cell (RBC) transfusions. In combination with incre - Deferasirox for managing iron overload in people with thalassaemia
Cochrane Systematic Reviews, 11-Aug-2017
Thalassaemia is a hereditary anaemia due to ineffective erythropoiesis. In particular, people with thalassaemia major develop secondary iron overload resulting from regular red blood cell transfusions. Iron chelation therapy is needed to prevent long-term - Deferasirox for managing transfusional iron overload in people with sickle cell disease
Cochrane Systematic Reviews, 29-Jun-2017
Sickle cell disease (SCD) is a group of genetic haemoglobin disorders, that occurs in about 2.2 per 1000 births worldwide. Increasingly, some people with SCD develop secondary iron overload due to occasional red blood cell transfusions or are on long-term - Deflation of gastric band balloon in pregnancy for improving outcomes
Cochrane Systematic Reviews, 19-Mar-2013
In line with the rise in the prevalence of obesity, an increasing number of women of childbearing age are undergoing laparoscopic adjustable gastric banding (LAGB), resulting in an increasing number of pregnancies with a band in place. Currently, there is - Degarelix for treating advanced hormone‐sensitive prostate cancer
Cochrane Systematic Reviews,
Degarelix is a gonadotropin-releasing hormone antagonist that leads to medical castration used to treat men with advanced or metastatic prostate cancer, or both. It is unclear how its effects compare to standard androgen suppression therapy. - Dehumidifiers for chronic asthma
Cochrane Systematic Reviews, 4-Jun-2014
Humidity control measures in the home environment of patients with asthma have been recommended, since a warm humid environment favours the growth of house dust mites. However, there is no consensus about the usefulness of these measures. - Dehydroepiandrosterone (DHEA) supplementation for cognitive function
Cochrane Systematic Reviews, 6-Nov-2008
In view of the theoretical rationale for beneficial effects of DHEA and DHEAS on cognitive function in ageing and dementia, we have undertaken a thorough investigation of well-conducted studies in this area. This will provide a basis for confirmation of a
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