PubMed Search for EE+ Evidence Summary

2014-12-10, updated 2017-3-1

The Evidence Summary tool is used in the process of updating Essential Evidence Topics. It searches for all recent articles within EE+ that may be relevant to a given EE Topic. In some cases, a search of PubMed is also performed to identify relevant recent studies. This document presents details of the PubMed search and records the search strategies that are used to search PubMed.

When a PubMed search is performed

When a manual Evidence Summary is performed, the user has the option of performing a PubMed search; this option is disabled by default. When an automated Evidence Summary is generated, a PubMed search will only be performed if the "annual" mode is specified.

Search string used in the PubMed search

Each EE Topic is indexed on a set of keywords; one or more of these keywords is flagged as “primary” keywords. When a manual Evidence Summary is performed, the user selects one or more of these keywords to use in generating the Evidence Summary ("primary" keywords are pre-selected defaults). For the PubMed portion of the search, the user has the option of using either the same selected keywords or a user-input search string in the PubMed search.

When an automated Evidence Summary is generated with the mode specified as "annual", the "primary" keywords are used in the PubMed Search.

If more than one keyword selected, the individual keywords are quoted and joined with the "OR" keyword.

Categories used in the PubMed search

Several independent PubMed searches are performed for different categories. The categories are documented below. Because each category search is independent, there may be some duplication of articles between the sections.

Presentation of PubMed search results

Each category that has one or more results is displayed as a separate section in the Evidence Summary. Results are sorted in reverse chronological order. Each section is restricted to the 20 most recent results.

PubMed search strategies

The Evidence Summary tool utilizes the Advanced PubMed Search (APMS) tool to perform the PubMed searches. The APMS tool is configured with a set of tiered search strategies for each category. Unless otherwise noted, all categories searched for Evidence Summaries are searched using the narrowest tier configuration of the APMS.

Common Strategies

There is a set of strategies that is shared among all categories.

hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour]) OR “Health Technol Assess”[jour] OR “J Invest Dermatol”[jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour]

These strategies are interpreted as follows.

  • Include only publications that have an abstract
  • Include only publications that are related to humans
  • Include only English-language publications
  • Include only publications from “High Impact” journals, defined as the Abridged Index Medicus (AIM) subset plus about 20 other selected journals.

Category Strategies

The following table documents the PubMed search strategies used for each category. SEARCH_STRING represents the search string used in the search. See Search string used in the PubMed search. Portions of the strategy that are common to all categories have been de-emphasized for readability.

Search Category Search Strategy
General Therapy (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” OR “J Invest Dermatol” OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour)AND ("randomized controlled trial"[pt] OR (randomized[tiab] AND controlled[tiab] AND trial[tiab]))
General Diagnosis (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour]) AND ("sensitivity and specificity"[MH] OR "likelihood ratio*"[tiab] OR (sensitiv*[tiab] AND specific*[tiab]) OR "predictive value*"[tiab] OR "ROC curve"[tiab] OR "area under the receiver operating"[tiab] OR AUROCC[tiab])
Prognosis (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour]) AND (prognos*[Title] AND cohort[Title/Abstract])
Natural History
(one of two strategies are considered, depending on the number of results)
(SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour]) AND ("natural history"[tiab] OR "usual course"[tiab] OR "typical course"[tiab] OR "expected course"[tiab])

(SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour])AND ("natural history"[tiab])
Prevention (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour])AND ("preventive medicine"[MH] OR "preventive health services"[MH] OR immunization*[MH] OR vaccination[MH] OR "health promotion"[MH] OR prevention[ti]) AND ("systematic review"[ti] OR guideline[tiab] OR meta-analysis[pt])
Clinical Decision Rules (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour])AND ("clinical prediction rule"[ti] OR "clinical score"[ti] OR "decision rule"[ti] OR "diagnostic rule"[ti] OR "diagnostic score*"[ti] OR "predictive rule*"[ti] OR "predictive score*"[ti] OR "prediction rule*"[ti] OR "prediction score*"[ti] OR "risk score*"[ti])
Systematic Reviews (SEARCH_STRING) AND hasabstract[text] AND humans[MH] AND English[lang] AND (jsubsetaim[text] OR "Ann Fam Med"[jour] OR "Br J Gen Pract"[jour] OR "Fam Pract"[jour] OR "J Gen Intern Med"[jour] OR "Acad Emerg Med"[jour] OR "Age Ageing"[jour] OR "Am J Emerg Med"[jour] OR "Am J Gastroenterol"[jour] OR "Birth"[jour] OR "BMC Fam Pract" OR "BMC Med"[jour] OR "Br J Psychiatry"[jour] OR "Diabetes"[jour] OR "Eur Heart J"[jour] OR "J Clin Epidemiol"[jour] OR "J Am Acad Dermatol"[jour] OR "J Am Geriatr Soc"[jour] OR "Lancet Infect Dis"[jour] OR "Scand J Gastroenterol"[jour] OR "Scand J Infect Dis"[jour] OR "Sex Transm Infect"[jour] OR "Stroke"[jour] OR "Thorax"[jour] OR “Health Technol Assess” [jour] OR “J Invest Dermatol” [jour] OR “Acad Emerg Med”[jour] OR “BMC Medicine”[jour]) AND ((systematic[sb] OR "systematic review"[ti] OR "meta-analysis"[ti] or "Meta-Analysis"[pt]) NOT "Cochrane Database Syst Rev"[tiab])