Showing 201-220 of 258 for: EBMG evidence summaries > Pharmacotherapeutics 
- Periconceptional supplementation with folate and/or multivitamins for preventing neural tube defects
EBMG evidence summaries, 20-Mar-2003
Periconceptional folate supplementation has a strong protective effect against neural tube defects.
- Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings
EBMG evidence summaries, 9-Jan-2007
Progressive withdrawal (over 10 weeks) appears to be more effective than abrupt withdrawal in the management of benzodiazepine mono-dependence.
- Pharmacological management of alcohol withdrawal
EBMG evidence summaries, 20-Mar-2003
Benzodiazepines are suitable agents for alcohol withdrawal. Phenothiazines alone may increase the risk for seizures.
- Pharmacological treatment for psychotic depression
EBMG evidence summaries, 11-May-2006
The combination of an antidepressant with an antipsychotic is probably not more effective than an antidepressant alone in the treatment of psychotic depression, but the combination therapy may be more effective than an antipsychotic alone.
- Platelet glycoprotein IIb/IIIa receptor antagonists in cardiovascular disease
EBMG evidence summaries, 18-Oct-2010
GP IIb/IIIa blockers reduce the risk of death and of death or MI at 30 days and 6 months in patients submitted to percutaneous coronary angioplasty. For patients with unstable angina or non-ST-segment elevation infarction, there is only slight advanta
- Preoperative vs. postoperative initiation of low-molecular-weight heparin prophylaxis
EBMG evidence summaries, 11-Aug-2003
Prophylaxis against deep vein thrombosis with LMWH may be more effective and safe when initiated pre-operatively rather than post-operatively.
- Pressurised metered dose inhalers versus other inhaler devices to deliver beta-2 agonists in asthma
EBMG evidence summaries, 20-Aug-2000
There are no significant differences for any important outcomes between standard CFC containing pMDI and other devices in the delivery of beta-2 agonist for non-acute asthma.
- Primary angioplasty versus intravenous thrombolysis for acute myocardial infarction
EBMG evidence summaries, 12-Nov-2008
Primary PTCA is more effective than thrombolytic therapy for the treatment of acute ST-segment elevation myocardial infarction. The benefit of primary angioplasty, over thrombolysis, depends on the additional time delay for angioplasty.
- Probiotics for maintenance of remission in Crohn's disease
EBMG evidence summaries, 25-Feb-2007
There is insufficient evidence on the effect of probiotics on Crohn's disease.
- Probiotics for the prevention of pediatric antibiotic-associated diarrhea
EBMG evidence summaries, 5-Dec-2011
Probiotics may be effective in prevention of pediatric antibiotic-associated diarrhea.
- Prophylactic oral betamimetics for reducing preterm birth in twin pregnancy
EBMG evidence summaries, 28-Dec-2005
Betamimetics may reduce the incidence of preterm labour in a twin pregnancy but there is no evidence on beneficial effects on pregnancy outcomes.
- Prophylaxis against deep vein thrombosis and pulmonary embolism using heparin or low molecular weight heparin in orthopaedic surgery
EBMG evidence summaries, 15-Jan-2006
Unfractionated and LMW heparins protect against lower limb deep venous thrombosis in orthopaedic surgery. Evidence is insufficient to confirm either protection against pulmonary embolism or overall benefit, or to distinguish between various applications o
- Proton pump inhibitors compared with H2-receptor antagonists in the treatment of duodenal ulcer and gastrooesophageal reflux disease
EBMG evidence summaries, 20-Mar-2003
Lansoprazole is more effective than ranitidine or famotidine in healing acute duodenal ulcer at 2 and 4 weeks.
- Proton pump inhibitors for acute peptic ulcer bleeding
EBMG evidence summaries, 25-Aug-2007
Proton pump inhibitor treatment in peptic ulcer bleeding appears to reduce rebleeding and surgical intervention rates compared with placebo or H2-receptor antagonist, but there is no evidence of an effect on mortality.
- Proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux
EBMG evidence summaries, 5-May-2010
Proton pump inhibitors are more effective than H2-receptor antagonists in empirical treatment of heartburn likely to be caused by gastro-oesophageal reflux and in endoscopy negative reflux disease.
- Quinolones for treatment of hospital-acquired pneumonia
EBMG evidence summaries, 21-Apr-2007
Quinolones are at least as effective as other antibiotics for hospital-acquired pneumonia.
- Rectal 5-aminosalicylic acid for induction of remission in distal ulcerative colitis
EBMG evidence summaries, 15-Apr-2010
Rectal 5-ASA is more effective than placebo or rectal corticosteroids for inducing symptomatic improvement and remission of mild to moderate distal ulcerative colitis.
- Remacemide for drug-resistant localization-related epilepsy
EBMG evidence summaries, 23-May-2012
Remacemide has a modest effect on seizure frequency and a significant withdrawal rate in patients with drug-resistant localization-related epilepsy.
- Reteplase for thrombolysis in acute myocardial infarction
EBMG evidence summaries, 11-Aug-2003
Reteplase appears to be at least as effective as alteplase.
- Reversal of left ventricular hypertrophy in essential hypertension
EBMG evidence summaries, 20-Mar-2003
Antihypertensive treatment reduces left ventricular mass. ACE inhibitors may be more effective than beta-blockers or diuretics.
